No unique dose adjustment suggested when tofacitinib coadministered with powerful CYP2C19 inhibitors; lower tofacitinib dose if coadministered with each average CYP3A4 and strong CYP2C19 inhibitors .posaconazole will improve the level or outcome of modafinil by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Watch.The identical